- 2011-2015: Erciyes University Medicine Faculty Ophthalmology Department// Resident 2015-2018: Nevsehir State Hospital // Ophthalmologist
- 2018-2021: Acibadem Private Hospital Kayseri// Ophthalmologist
- 2021- 2022: Acibadem University Atakent Hospital Istanbul // Ophthalmologist
Education:
- Postgraduate: Erciyes University Ophthalmology Department (2011-2015) Graduate: Erciyes University Medicine Faculty (2004-2010)
- High School: Fatma-Kemal Timucin Anatolian High School (2000-2004)
Awards and Certificates:
– Rank the First in Graduation of Erciyes University Medicine Faculty-2010
-Turkish Ophthalmology Association March Symposium Poster Award Adana-2014
-European Board of Ophthalmology- 2015
-Journal of Retina-Vitreous Scientific Publication Encouragement Award 2015
-Stem Cell and Cellular Therapies Society (ISSCA) Special Award- 2019
-International Council of Ophthalmology -Visual Sciences and Optics 2019
-Clinic Ophthalmology 2020
-Advanced 2020 -Turkish Ophthalmology Society Qualification Certificate -2022
WORKS:
The Articles published in international internationally acclaimed journals:
1. Oner A, Gonen ZB, Sinim N, Cetin M, Ozkul Y. Subretinal adipose-tissue derived mesenchymal stem cell implantation in advanced stage retinitis pigmentosa: A Phase I clinical safety study. Stem Cell Research and Therapy. 2016 Dec 1;7(1):178.
2. Oner A, Gonen ZB, Sevim DG, Sinim Kahraman N, Unlu M. Suprachoroidal Adipose Tissue-Derived Mesenchymal Stem Cell Implantation in Patients with Dry-Type Age-Related Macular Degeneration and Stargardt’s Macular Dystrophy: 6-Month Follow-Up Results of a Phase 2 Study. Cell Reprogram. 2018 Dec;20(6):329-336.
3. Kahraman Sinim N, Öner A. Stem Cell Treatment in Degenerative Retinal and Optic Nerve Diseases. Trakya University Journal of Natural Sciences.2019. 20(Special Issue): S11- S16.
4. Oner A, Gonen ZB, Sevim DG, Sinim Kahraman N, Unlu M. Six-month results of suprachoroidal adipose tissue-derived mesenchymal stem cell implantation in patients with optic atrophy: a phase 1/2 study. Int Ophthalmol. 2019 Dec;39(12):2913-2922.
5. O ner A, Gonen ZB, Sevim DG, Sinim N, Cetin M, Ozkul Y. First-Year Results of Subretinal Mesenchymal Stem Cell Implantation in Severe Retinitis Pigmentosa. Oct. 2019 J Stem Cell Res Ther. 9:454.
6 . Kahraman Sinim N, Sevim DG, Oner A. Cross-Validation of the Turkish Version of the 28-Item Impact of Vision Impairment Profile test. Open Journal of Ophthalmology.2019
9;194-202.
7. Kahraman Sinim N, Oner A. Subtenon Injection of Autologous Platelet-Rich Plasma in Retinitis Pigmentosa: Is It a New Therapeutic Option? Open Journal of Ophthalmology. 2020 10 (1):77-88.
8. Sinim Kahraman N, Oner A. Effect of Transcorneal Electrical Stimulation on Patients with Retinitis Pigmentosa. J Ocul Pharmacol Ther. 2020 Oct;36(8):609-617.
9. Kahraman Sinim N, Oner A. Umbilical cord-derived mesenchymal stem cell implantation in retinitis pigmentosa: a 6-month follow-up results of a phase 3 trial. Int J Ophthalmol. 2020 Sep 18;13(9):1423-1429
10. Kahraman NS, Gonen ZB, Sevim DG, Oner A. First-Year Results of Suprachoroidal AdiposTissue-Derived Mesenchymal Stem Cell Implantation in Degenerative Macular Diseases. Int J Stem Cells. 2020 Oct 31. 14 (1):47-47,
11 1. Kahraman NS, Öner A. Umbilical cord-derived mesenchymal stem cell implantation in patients with optic atrophy. Eur J Ophthalmol. 2021 Nov;31(6):3463-3470.
12. Oner A, Kahraman NS. Does Stem Cell Implantation Have an Effect on Severity of Retinitis Pigmentosa: Evaluation with a Classification System? Open Journal of Ophthalmology, 2021 Feb; 11, 36-48.
13. Oner A, Kahraman NS. Comparison of Suprachoroidal and Subtenon Stem Cell Delivery Methods in Patients with Retinitis Pigmentosa. J Stem Cell Ther Res,2021; 1(1): 1-8.
14. Kahraman NS, Oner A. The Evaluation of Vision-Related Quality of Life in Patients with Retinitis Pigmentosa after Suprachoroidal Umbilical Cord Derived Mesenchymal Stem Cell Treatment. Open Journal of Ophthalmology, 2021; 11, 203-213.
15. Altinisik M, Kahraman NS, Kurt E, Mayali H, Kayikcioglu O. Quantitative analysis of early retinal vascular changes in type 2 diabetic patients without clinical retinopathy by optical coherence tomography angiography. Int Ophthalmol. 2022 Feb;42(2):367-375.
16. Oner A, Kahraman NS. Suprachoroidal umbilical cord-derived mesenchymal stem cell implantation for the treatment of retinitis pigmentosa in pediatric patients American Journal of Stem Cell Research 2023, 5(1): 1-7
17. Sinim Kahraman N, Özgüç Çalışkan B, Kandemir N, Öner A, Dündar M, Özkul
Y. ABCA4 variant screening in a Turkish cohort with Stargardt disease. Ophthalmic Genet. 2024 Feb 18:1-7. doi: 10.1080/13816810.2024.2313490.
Reports are made at international scientific meetings and published in declaration books;
1.Oner A, Sinim N, Polat OA. Central choroidal and macular thickness in healthy Turkish subjects measured use spectral-dominant optical coherence tomography. The 3rd Congress on Controversies In Ophthalmology. 22-24 March 2012; İstanbul, Turkey.
2. Oner A, Agadayi A, Sinim N, Karaca C. Differentiating optic disc edema from optic nerve head drusen with spectral-domain spectral-domain optical coherence tomography. 13th Euretina Congress 26- 29 September 2013; Hamburg g, Germany.
3. Oner A, Polat OA, Sinim N. Choroidal Tage-RelatedDry Age-Related Macular Degeneration. 14th Euretina Congress 10-14 September 2014; London, UK.
4. Oner A. Sinim N, Demirel S. The Effects Of Half- Influence Photodynamic Therapy to Central Choroidal Thickness in Chronic Central Serous ChorioretinopathyAnnualnts. ASRS Annual Meeting. 10-13 JuAustriaVienne- AusturiaAustria.
5. Oner A, Gonen ZB, Sinim N, Cetin M, Ozkul Y. Subretinal adipose-tissue derived mesenchymal stem cell implantation in advanced stage retinitis pigmentosa: A Phase I clinical safety study. 16th Euretina Congress 8-12 September 2016; Copenhagen, Denmark.
6. Oner A, Gonen ZB, Sevim DG, Sinim N, Cetin M, Ozkul Y.First-year-year results of subretinal adipose tissue derivedtissuederived tissue-derived tissue-derived tissue-derived mesenchymal stem cell implantation in advanced stage retinitis pigmentosa. 18th Euretina Congress, 20-23 September 2018, Vienna, Austria (Oral presentation)
7. Kahraman NUmbilicalA. Can Umbilical cord-derived Mesenchymal Stem Cells Be Used In Retinal Diseases: A Case Presentation of Leber Congenital Amaurosis. 3. Stem cell and cellular therapies congress 12-14 April 2019. İstanbul. (Oral presentation)
8.Oner A, Kahraman NS, Gonen ZB. Suprachoroidal mesenchymal stem cell implantation in patients with optic neuropathy. 3. Stem cell and cellular therapies congress 12-14 April 2019. İstanbul. (Oral presentation)
9. Oner A, Kahraman NS, Gönen Zyearsesults of 4 year4-year follow-ups after subretinal mesenchymal stem cell implantation in two patients with advanced-stage retinitis pigmentosa. 3. Stem cell and cellular therapies congress 12-14 April 2019.İstanbul. (Oral presentation)
10. Kahraman NS, Oner A. A new therapeutic option for retinitis pigmentosa: subtenon injection of autologous platelet-rich plasma. 19th Euretina Congress 4-8 September 2019; Paris, France. (Oral presentation)
11. Oner A, Kahraman NS, Hekmatullah Hekmat, Unlu M. Correlation between Optical Coherence Tomography and Multifocal Electroretinogram Findings in Patients with Chronic Central Serous Chorioretinopathy Who Underwent Photodynamic Therapy. 19th Euretina Congress 4-8 September 2019; Paris, France. (Oral presentation)
12. Kahraman NS, Oner A, Gonen ZB, Sevim DG, Unlu M. Mesenchymal stem cell implantation in advanced stage retinitis pigmentosa: 6-month results of a phase 2 study. 19th Euretina Congress 4-8 September 2019; Paris, France. (Oral presentation)
13.Kahraman NS, Oner A, Sevim DG. Delivery of the stem cells to the retina. World Ophthalmology Congress 2020; 26-29 June. Virtual. (Oral presentation)
14. Oner A, Kahraman NS, Sevim DG. The impact of retinal diseases on the IVI questionnaire on VRQoL in the Turkish population. World Ophthalmology Congress 2020; 26-29 June. Virtual.
15. Oner A, Kahraman NS. Suprachoroidal mesenchymal stem cell implantation in pediatric patients with degenerative retinal diseases:6-month follow-up results in Euretina Congress 9- 12 September 2021. Virtual. (Oral presentation)
16. Oner A, Kahraman NS, Ovalı E. Suprachoroidal implantation of 3-dimensional spheroid umbilical cord-derived mesenchymal stem cell in a retinitis pigmentosa patient. 22. Euretina Congress 1-4 September 2022 Hamburg Germany.
17. Kahraman NS, Oner A. Clinical and Genetical Characteristics of Stargardt Diseases. 22. Euretina Congress 1-4 September 2022 Hamburg Germany.
The articles published in nationally acclaimed journals:
1. Polat OA, Oner A, Arda H, Sinim N, Gümüs K. Ocular Trauma in Paintball Game. Journal of Retina-Vitreous, 20:225-229, 2012.
2. Polat OA, Sinim N, Oner A. Central Choroidal and Macular Thickness in Healthy Turkish Subjects Measured Using Spectral-Domain Optical Coherence Tomography. Journal of Retina Vitreous 20: 95-98, 2012
3. Sinim N, Karaca C, Demirel D, Polat OA, Oner A. The evaluation of central macular and choroidal thickness in myopic subjects spectral-dominant optical coherence tomography. Journal of Retina Vitreous, 21: 189-192, 2013.
4. Polat OA, Sinim N, Oner A Choroidal Thickness in Dry Age-Related Macular Degeneration. Journal of Retina Vitreous. 21: 265-268, 2013.
5. Oner A, Deliktas G, Arda H, Sinim N, Gumus K, Mirza E, Karakucuk S. Diurnal Variation of Central Choroidal Thickness in Healthy Turkish Subjects MeasureSpectral-Domainomain Optical Coherence Tomography. Journal of Retina Vitreous, 22: 204-208, 2014.
6. Oner A, Yıldırım Y, Sinim N. Anterior Chamber Migration of a Dexamethasone Implant in a Patient with a Scleral-Fixated Ocular Lens. Journal of Retina Vitreous. , 191-194, 2015.
7. Oner A, Ağadayı A, Sinim N. Differentiating Optic Disc Edema From Optic Nerve Head Drusen Spectral-Domainomain Optical Coherence Tomography Journal of Retina Vitreous. 2015; 23:141-144.
8.Ersekerci TK, Sonmez S, Sinim N, Oner A. Three Cases of SMaculopathypathy Caused By The Light of a New Military Device. Journal of Retina Vitreous 2015-12-23;23: 220-22 3
9. Oner A, Sinim N. Ranibizumab treatment in type 1 diabetic patient for macular
edema during lactation: A case report. Journal of Retina Vitreous 2015; 23:56-59 Ozel Sayı
10. Oner A, Sinim N, Parmaksız N. The Effects of Photodynamic Therapy to Central Choroidal Thickness in Chronic Central Serous Chorioretinopathy Patients. Journal of Retina Vitreous 2016; 24: 52-56.
11. Oner A, Sinim N, Arda H, GümüS K, KaraküCük S, Mirza E. Central Choroidal Thickness in Eyes With Central Serous Chorioretinopathy: The effect of disease activity.Journal of Retina Vitreous 2016; 24:
12. Sinim N, Oner A. Long term Complications of Premature of Retinopathy. Journal of Retina Vitreous 2018; 27: 196-20 0.
13. Kahraman Sinim N, Karaküçük S. Posterior Segment Effects of Prostaglandin Analogues. Journal of Retina Vitreous 2020; 29: 30-34.
14. Oner A, Kahraman NS. Retina transplantation, stem cell and gene therapies in Retinitis Pigmentosa. Güncel Retina 2021; 5 (2): 131-139
15.Oner A, Kahraman NS. Treatment options in hereditary retinal diseases. Turkiye Klinikleri Special Issue Ocular Genetics. 2021; 49-56.
16. Sinim Kahraman N, Öner A, Özkul Y, Dündar M. Frequency of RPE65 Gene Mutation in Patients with Hereditary Retinal Dystrophy. Turk J Ophthalmol 2022; 52:270-275
17. Sinim Kahraman N, Öner A. The Effects of Central and Peripheral Visual Field Loss on Quality of Life Comparison. MN Ophthalmology. 2022; 29(4):238-244
18. Öner A, Kahraman NS. Evaluation of Full-Field Stimulus Threshold Test Results in Retinitis Pigmentosa: Relationship with Full-Field Electroretinography, Multifocal Electroretinography, Optical Coherence Tomography, and Visual Field. Turk J Ophthalmol 2024;54:23-31.
Reports are made at national scientific meetings and published in declaration books:
1.Sinim N, Polat OA, Oner A. A Case Report ChoronicChronic Renal Failure Diagnosis with Ocular Symptoms. 46. Turkish Ophthalmology Association National Congress, 2012, Antalya.
2.Sinim N, Evereklioğlu C. Case Report BCC 46. Turkish Ophthalmology Association National Congress, 2012, Antalya.
3. Oner A, Sinim N, Polat OA, Arda H, GümüS K, KaraküCük S, Mirza E. Choroidal Thickness in Drage-Related Macular Degeneration. 46. Turkısh Ophtalmalogy Association National Congress, 2012, Antalya.
4. Oner A, Agadayı A, Sinim N, Karaca C Differentiating Optic Disc Edema From Optic Nerve Head Drusen with spectral-domain Optical Coherence Tomography. 47. Turkısh Ophtalmalogy Association National Congress, 2013, Antalya.
5. Sinim N, Karaca C, Polat OA, Oner A. The evaluation of central macular and choroidal thickness in myopic subjects with spectraldomainndomain optical coherence tomography. 47. Turkısh Ophtalmalogy Association National Congress, 2013, Antalya. (Oral Presentation)
6. Demirel D, Sinim N, Polat OA, Oner A. Posterior microftalmi: Case Report. 47. Turkısh Ophtalmalogy Association National Congress, 2013, Antalya.
7. Polat OA, Sinim N, Oner A. Choroidal Thickness in DryAge-Related Macular Degeneration. Turkish Ophtalmology Association March Symposıum, Adana-2014
8. Sinim N, Oner A. The Effects of Photodynamic Therapy to Central Choroidal Thickness in Chronic Central Serous Chorioretinopathy Patients. 48. Turkısh Ophtalmalogy Association National Congress, 2014, Antalya. (Oral Presentation)
9. Oner A, Sinim N. Three Cases of Solar Maculopathyy Caused By The Light of a New Military Device. 48. Turkısh Ophtalmalogy Association National Congress, 2014, Antalya.
10. Sinim N, Oner A. Bilateral intravitreal deksametazon implant (Ozurdex) on 3 Diabetic macular edema patients who resistant to Anti-VEGF. 48. Turkısh Ophtalmalogy Association National Congress, 2014, Antalya.
11.Yıldırım Y, Sinim N, Oner A. Anterior Chamber Migration of a Dexamethasone Implant. 48. Turkısh Ophtalmalogy Association National Congress, 2014, Antalya.
12.Sinim N, Karakücük S, Mirza GE, Arda H, Oner A. The Effects of the Prostaglandin Analogs on the Anterior and Posterior Segment of the Eye 49. Turkish Ophthalmology Association National Congress 2015, İstanbul.
13.Kahraman Sinim N, Oner A. The results of suprachoroidal umbilical cord umbilical cord- derived mesenchymal stem cell therapy in retinitis pigmentosa 123 cases. TOD 53rd National Ophthalmology Congress, 06-10 November 2019. Antalya. (Oral Presentation)
14. Öner A, Kahraman NS, Gönen ZB. The results of suprachoroidal mesenchymal stem cell therapy in optic atrophy. TOD 53. National Ophthalmology Congress. 06-10 November 2019, Antalya. (Oral Presentation)
15.Öner A, Kahraman NS, Sevim DG. Quality of life with 28-question IVI test in patients with retinitis pigmentosa. TOD 53. National OphtjalmologyOphthalmology Congress. 06-10 November 2019, Antalya.
16. Kahraman Sinim N, Oner A Subtenon injection of autologous platelet-rich plasma in retinitis pigmentosa, TOD 53rd National Ophthalmology Congress, 06-10 November 2019 Antalya.
17. Kahraman Sinim N, Oner A. Quality of life with 28-question IVI test in patients with- related macular degeneration. TOD 54th National Ophthalmology Congress, 9-13 December 2020. Virtual.
18. Oner A, Kahraman NS. Grading according to the severity of the disease in retinitis pigmentosa and the criteria used in grading. TOD 54th National Ophthalmology Congress, 9- 13 December 2020. Virtual.
19. Kahraman NS, Oner A. Umbilical cord-derived cord-derived mesenchymal stem cell implantation in patients with optic atrophy. Istinye University Stem cell and Tissue Engineering Symposium. 27-28 February 2021. Virtual. (Oral Presentation)
20. Oner A, Kahraman NS. Suprachoroidal umbilical cord derived mesenchymal stem cell implantation in patients with retinitis pigmentosa: 6-month results of a phase 3 study. Istinye University Stem cell and Tissue Engineering Symposium. 27-28 February 2021. Virtual. (Oral Presentation)
21. Kahraman NS, Oner A, Ozkul Y, Dündar M. Genetic profile of our pigmentary retinopathy cases. 3-7 November 2021, Antalya. (Oral Presentation)
22. Kahraman NS. Electrophysiology panel. Case reports. 3-7 November 2021, Antalya. (Oral Presentation)
23. Kahraman NS. Electrophysiology panel. Electrophysiological tests in hereditary optic neuropathies. TOD March symposium, 22-24 April 2022, Trabzon (Oral Presentation)
24. Öner A, Kahraman NS. Full-field stimulus test results in the cases of the retinitis pigmentosa. TOD 44. Spring Symposium. 13-15 May 2022 Istanbul (Oral Presentation)
25. Öner A, Kahraman NS, Sevik MO, Tülü K, Şahin Ö, Özsoy SD. Evaluation of the mood status of the patients with retinitis pigmentosa with Beck depression scale. TOD 56th National Ophthalmology Congress, 2-6 November 2022. Antalya.
26. Kahraman NS, Öner A, Özkul Y, Dündar M. Clinical and genetic characteristic of our cases with Bietti crystalline dystrophy. TOD 56th National Ophthalmology Congress, 2-6 November 2022. Antalya.
BOOK CHAPTERS:
1. Osman Ahmet Polat, Neslihan Sinim, Ayşe Öner. Phakomatoses. Pediatric Ophthalmology and Strabismus. Basic and Clinical Sciences Course. Translation Editor: Pınar Aydın O’Dwyer Güneş Medical Bookstore, ANKARA. Page: 363-381. (Translation), 2012
2. Neslihan Sinim. Infective Inflammatory Eye Diseases. Intraocular Inflammation and Uveitis. Basic and Clinical Sciences Course. Translation Editor: Pınar Aydın O’Dwyer Güneş Medical Bookstore, ANKARA. 2013 Page: 197-211. (Translation), 2012.
3. Neslihan Sinim, Ayşe Öner. Ophthalmologic Emergency. Emergency Medicine Pocket Book. Editor: Zeynep Kekec. Academician Medical Bookstore. ANKARA. Page: 217-227, 2017. ISBN: 9786052588321
4. Karakucuk MS, Kahraman Sinim N, Alpoğan Oksan. Ophthalmological Problems of Athletes. Clinical Sports Medicine. Güneş Medical Bookstore. Ankara 2020. Pages: 195-199. ISBN: 9789752778177
5. Neslihan Sinim Kahraman. Use of Electrophysiology tests in Animal Studies. Ocular Electrophysiology. Editor: Dr. Banu Turgut Bozkurt. Anadolu Bookstore, Ankara 2021. Page: 257-263. ISBN: 978-605-61013-8-0